1823
Fort St. John is closed following an armed conflict with local First Nations.
1828
HBC post journals from Dunvegan begin reporting a decline in population among the Dane-zaa of the Peace River due to sickness and death, a trend that continues into the next decade.
1838
Census records indicate that Iroquois, Salteaux, Cree and Metis hunters begin moving with their families from the plains to the Peace River despite protests from the Dane-zaa. The newcomers bring smallpox to the area.